More information
| Name | SEVENS |
|---|---|
| Aliases | None |
| Description | SEVENS database includes G-protein coupled receptors (GPCR) genes with seven transmembrane helices, that are identified with high accuracy from complete genomes of 32 eukaryotes, by a pipeline integrating such software as a gene finder, a sequence alignment tool, a motif and domain assignment tool, and a TMH predictor. |
| Type | DB |
| Main Institutes of management | Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST) |
| Country of the Institute | Japan |
| URL of the site | http://sevens.cbrc.jp/ |
| Interface | GUI |
| Input example | Select species and input the keyword in the text box, and then push the "submit" button. You can select Chromosome Number, Exon Number, Protein Length, Pseudogene and Family. |
| Amount of the all data for download（Mbyte） | Method to obtain the all data. | 7,000 | Not available. |
| External resources (databases) in building the product. | NCBI|KEGG|SWISS-Prot|Pfam |
| Data type | Ptotein-sequence amino acid sequence |
| Biological species in the main concern | All species |
| Conditions of use | Attribution&Noncommercial&Share Alike User account is not required. |
| Frequency of updates (in last two years) | 2 |
| Last date of updates (date of confirmation) | 2010/04/28 (2010/05/10) |
| Main IDs used in the products | CBRC-species-2digit numbers-4digit numbers |
| How to make a link to get access to each IDs. | http://sevens.cbrc.jp/detail.php?db=[species]&chr=[chromosome_number]&l=1&r=1053750&twin=0&id=[ID] |
| external databases to which this database/tool have links | ExPASy Proteomics Server(http://www.expasy.org/), NCBI(http://www.ncbi.nlm.nih.gov/), Pfam(http://pfam.sanger.ac.uk/) |
| Published papers (PubMed IDs) | PMID: 16126348, Automatic gene collection system for genome-scale overview of G-protein coupled receptors in eukaryotes. Ono Y, Fujibuchi W, Suwa M. Gene. 2005 Dec 30;364:63-73. |
| Project name | KAKENHI (208059) |
|---|---|
| Area | Genome Informatics |
| Purpose | In order to support high-throughput screening for ligands of G-protein coupled receptors (GPCRs) by using bioinformatics technology, we introduce a database (SEVENS) with genome-scale annotation. |
| Introduction | To perform an overview of the GPCR universe, it is necessary to treat a large data space, which should include not only the expressed sequences but also the newly identified sequences that cannot be detected by experiments, although they definitely exist on the genome sequence and are just waiting for the opportunity to express their functions. For this purpose, we have been developed SEVENS which includes GPCR genes that are identified with high accuracy from complete genomes of eukaryotes. |
| Keyword | GPCR|Genome|Function|annotation| |
| Patent (Japan, overseas) | なし |
| Product (Database, Tool) | Nothing |