More information XML output
| Name | Integrated Cancer Genome Database |
|---|---|
| Aliases | None |
| Description | In order to identify genes responsible for drug sensitivities and side effects of anti-cancer drugs, the project genotyped about 3,000 SNPs in candidate genes for breast cancer patients by the Invader method. The database stores genotype frequencies of these SNPs and their relation with drug sensitivities and side effects. The candidate genes include 512 genes related to pharmacokinetics, DNA repair, apotosis, cell cycle control, angiogenesis, and inflammation. The database provides genotype frequencies of these SNPs and it is downloadable. |
| Type | DB |
| Main Institutes of management | The Genome Center of Japanese Foundation for Cancer Research |
| Country of the Institute | Japan |
| URL of the site | http://genomecenter.jfcr.or.jp/genomedb/ |
| Interface | Search site |
| Input example | ABCA (gene name search) |
| Keyword |
Under investigation
|
| Amount of the all data for download（Mbyte） | Method to obtain the all data. | 0.4 | Select "CSV output" when all data of all genes are displayed. |
| External resources (databases) in building the product. | Unable to set hyperlinks to individual data |
| Data type | |
| Biological species in the main concern |
Human
|
| Conditions of use | Copyrighted by JBIC and Genome Center of JFCR |
| Frequency of updates (in last two years) | 0 |
| Last date of updates (date of confirmation) | 2006/02/27 (2008/10/15) |
| Main IDs used in the products | HUGO Gene Symbol | dbSNP rs# |
| How to make a link to get access to each IDs. | Under investigation |
| external databases to which this database/tool have links | Under investigation |
| Published papers (PubMed IDs) | Under investigation |
| Project name | Genome Diversity Project |
|---|---|
| Area | drug discovery |
| Purpose | This project is being undertaken to collect genetic polymorphism information relating to model diseases (such as autoimmune diseases, diabetes, eating disorders, cancer, etc.). It also aims to develop a technique to associate disease-related or drug sensitive genes with the differences in their expression, for example, why some people have a particular medical condition such as an allergy and others do not. The results will be used to develop analysis technology and create a useful database. (Ref. http://www.nedo.go.jp/kankobutsu/pamphlets/kouhou/outline2005.pdf (P. 15))1 |
| Introduction | It also aims to develop a technique to associate disease-related or drug sensitive genes with the differences in their expression, for example, why some people have a particular medical condition such as an allergy and others do not. The results will be used to develop analysis technology and create a useful database. |
| Keyword | genome-wide association study | microsatellite | SNP | disease | polymorphism | genetic statistics |
| Patent (Japan, overseas) | JP2004325419(A) | JP2005038279(A) | JP2005085063(A) | JP2005092719(A) | JP2005129024(A) | JP2005278479(A) | JP2005312364(A) | JP2006024063(A) | JP2006048429(A) | JP2006065529(A) | JP2006079334(A) | JP2006277611(A) | JP2007074916(A) | JP2007097486(A) | JP2007233485(A) | JP2008021028(A) | JP2004192018(A) | JP2004173505(A) | JP2004272350(A) |
| Archives | |
| Product (Database, Tool) | Nothing |
